Washington, April 12 (IANS): US President Barack Obama Friday nominated a new department secretary to lead the federal health reform programmes, accepting resignation of his Health and Human Services Secretary Kathleen Sebelius.

Obama nominated the White House budget office director Sylvia Matthews Burwell to replace her, Xinhua reported.

The Harvard-educated Burwell was confirmed as White House budget director last April, and previously worked at the top levels of major foundations, including as president of the Walmart Foundation.

"If confirmed by the Senate, I look forward to carrying on the important work of ensuring that children, families, and seniors have the building blocks of healthy and productive lives, whether it's through implementing the Affordable Care Act, supporting affordable childcare, or finding new frontiers to prevent and treat disease," Burwell said.

Sebelius announced her resignation just about two weeks after the ObamaCare enrollment period drew to a close March 31, which attracted more than 7 million people signing up under the Affordable Care Act exchanges.

Sebelius, having served five years with the president, was among the longest-serving Cabinet secretaries in the administration.