Diabetes drug may help treat breast cancer


Beijing, March 19 (IANS): Chinese researchers have found that a drug used to treat diabetes could be effective against a form of breast cancer.

Over 70,000 people die from breast cancer in China every year, according to the national cancer centre.

Triple-negative breast cancer is particularly aggressive among the four clinical subtypes of breast cancer, Xinhua news agency quoted Dong Chenfang, a professor at Zhejiang University School of Medicine, as saying.

It has a tendency to quickly spread or metastasize to the brain and lungs. There are currently no effective targeted therapies for this form of breast cancer, which is therefore often fatal, he said.

Dong and his colleagues found that the levels of a metabolic enzyme called AKR1B1 were significantly elevated in triple-negative breast cancer cells and that this was associated with increased rates of metastasis and shorter survival.

The researchers also found epalrestat, a drug that inhibits AKR1B1 and is approved in Japan to treat diabetic complications, was able to block the growth and metastasis of the cancer cells.

Dong said the finding is still in the experimental stage.

  

Top Stories


Leave a Comment

Title: Diabetes drug may help treat breast cancer



You have 2000 characters left.

Disclaimer:

Please write your correct name and email address. Kindly do not post any personal, abusive, defamatory, infringing, obscene, indecent, discriminatory or unlawful or similar comments. Daijiworld.com will not be responsible for any defamatory message posted under this article.

Please note that sending false messages to insult, defame, intimidate, mislead or deceive people or to intentionally cause public disorder is punishable under law. It is obligatory on Daijiworld to provide the IP address and other details of senders of such comments, to the authority concerned upon request.

Hence, sending offensive comments using daijiworld will be purely at your own risk, and in no way will Daijiworld.com be held responsible.