Daijiworld Media Network - Florida

Florida, Mar 14: A high-fat, high-sugar Western diet may significantly raise the risk of lung cancer, according to a new study published in Nature Metabolism. Researchers have long studied the link between diet and cancers affecting organs like the liver and pancreas, but lung cancer has rarely been considered a diet-related disease until now.

Dr Ramon Sun, associate professor at the University of Florida, explained, "Lung cancer has not traditionally been thought of as a dietary-related disease. However, our study shows that diet can play a crucial role."

The research focused on glycogen, a glucose-based storage molecule that accumulates at high levels in many cancers. In lung cancer, glycogen acts as a metabolic driver, fueling tumor growth. Lab studies showed that mice fed a high-fat, high-fructose Western diet developed more aggressive lung tumors. Conversely, when glycogen levels dropped, tumor growth slowed.

“Glycogen is an exceptionally good predictor of tumor growth and survival in lung cancer patients,” Dr Sun noted.

The researchers emphasized the need for greater public awareness and policy-driven strategies to promote healthier diets, much like the global anti-smoking campaigns. They recommended prioritizing a nutrient-rich diet, staying active, and reducing alcohol intake as key strategies for long-term health.