Daijiworld Media Network - Thiruvananthapuram
Thiruvananthapuram, Feb 28: Chronic Kidney Disease (CKD) often progresses quietly, affecting nearly 10% of the global population before symptoms appear. While diabetes and high blood pressure remain the leading causes, nephrology experts warn that several lesser-known factors are silently damaging kidneys.
Dr Mohammed S. Khan, Associate Consultant at KIMSHEALTH, Thiruvananthapuram, said, “The global kidney disease crisis forces us to look beyond the usual suspects onto emerging threats caused by environment, lifestyle, and genetics.”

Dr Gireesh M. S., HOD and Consultant at Ramaiah Memorial Hospital, added that nearly one in four adults may have some degree of kidney impairment, underscoring the need for early detection.
Key emerging risks include:
• Obesity: Excess weight forces kidneys to overwork, leading to scarring and reduced filtration. Lifestyle changes such as weight control and balanced diets can protect kidney health.
• Smoking: Nicotine and toxins in cigarettes reduce blood flow to kidneys and accelerate damage. Quitting can slow CKD progression.
• CKDu (Chronic Kidney Disease of Unknown Etiology): Affecting young farmers and laborers in regions like Andhra Pradesh, Telangana, Kerala, Goa, Odisha, Maharashtra, and Chhattisgarh, CKDu may be linked to heat stress, dehydration, agrochemicals, and heavy metals. Regular screening in hotspots is vital.
• Frequent painkiller use: Over-the-counter NSAIDs can quietly harm kidneys when used repeatedly. Traditional or indigenous medications with undisclosed ingredients may pose similar risks.
• Supplements: Unregulated high-protein or fat-burning supplements can stress kidneys, particularly in individuals with undiagnosed kidney issues.
• Recurrent UTIs and kidney stones: These can lead to permanent kidney scarring if untreated.
• Genetics and autoimmune conditions: Family history and conditions like lupus contribute to 20–25% of CKD cases.
Dr Khan emphasized early detection, while Dr Gireesh stressed, “Regular check-ups and screenings are key. Many kidney problems remain hidden until significant damage occurs, so proactive health monitoring is crucial.”
Both experts urge awareness of these silent threats to kidney health, especially for individuals with obesity, family history, frequent painkiller use, or occupational exposures.