Diabetes drug can reduce risk of heart and kidney disease


New York, June 14 (IANS): An injectable drug widely used to lower blood sugar levels in type 2 diabetes, can also reduce the risk of dying from heart disease and advanced kidney disease, finds a new study.

The findings showed that taking liraglutide drug can safely and effectively decrease by 13 per cent the overall risk of heart attack, stroke or cardiovascular death, which is the major cause of mortality in people with Type 2 diabetes. 

Also, liraglutide lowered the risk of cardiovascular mortality by 22 per cent and the risk of all-cause mortality by 15 per cent.

In addition, it also decreases the risk of new evidence of advanced kidney disease by 22 per cent.

"This is the first diabetes drug that has shown across-the-board benefits for cardiovascular diseases and this suggests it plays a role in treating atherosclerosis, which leads to heart attacks and strokes," said John Buse from the University of North Carolina in the US.

Liraglutide works in the pancreas to stimulate insulin secretion and reduce the production of an anti-insulin hormone -- known as glucagon -- which raises the concentration of blood glucose. 

Liraglutide also works in the brain to reduce appetite and increase satiety -- the sensation of feeling full.

Type 2 Diabetes affects more than 370 million people worldwide, according to the World Health Organisation. 

For the results, published in the New England Journal of Medicine, the team included 9,340 adults with Type 2 diabetes who were at high risk of heart disease for a global clinical trial that lasted more than three years. 

About half of the participants were given liraglutide, and half were in the placebo group. 

Both groups of patients were prescribed medications to address associated health problems, such as high blood pressure and high cholesterol.

  

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Comment on this article

  • sara,

    Tue, Jun 14 2016

    In June of 2015, it was discovered that I had type 2 diabetes. By the end of the month, I was given a prescription for Metformin. I stated the ADA diet and followed it completely for several weeks but was unable to get my blood sugar below 140. With no results to how for my hard work, I panicked and called my doctor. His response? Deal with it. I began to feel that something wasn’t right and do my own research. Then I found Rachel’s blog http://myhealthlives.com/i-finally-reversed-my-diabetes/ . I read it from cover to cover and I started the diet and by the next morning, my blood sugar was 100. Since then, I have a fasting reading between the mid 70s and 80s. My doctor was so surprised at the results that, the next week, he took me off the Metformin. I lost 30 pounds in the first month and lost more than 6 inches off my waist and I’m able to work out twice a day while still having lots of energy. The truth is we can get off the drugs and help myself by trying natural methods

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