Latest Ebola data rules out rapid mutation


Beijing, May 14 (IANS): The Ebola virus evolved as it spread through West Africa last year -- but its mutation rate did not accelerate as some had thought, says an analysis of genetic sequence data.

The data offers reassurance that the scope of the current epidemic did not make it possible for the virus to evolve into a more virulent or deadlier form.

To reach this conclusion, a team led by Wu-Chun Cao, epidemiologist at the State Key Laboratory of Pathogen and Biosecurity in Beijing sequenced 175 Ebola virus genomes from people who were infected with the virus, including some who died.

Cao's group combined the data with sequences found by Pardis Sabeti, computational geneticist at the Broad Institute in Cambridge, Massachusetts.

The combined data allowed Cao to track how the Ebola virus changed as it spread east to west across Sierra Leone. Ebola entered the country in May and reached the capital city, Freetown, in July.

The analysis found that the virus evolved as it spread to new areas but it did not change at a faster rate than it has in past outbreaks. There is no evidence that Ebola evolved harmful mutations as it spread through Sierra Leone.

"This is just the virus doing what it does," said David Robertson, computational and evolutionary biologist at University of Manchester.

The study appeared in the journal Nature.

 

  

Top Stories


Leave a Comment

Title: Latest Ebola data rules out rapid mutation



You have 2000 characters left.

Disclaimer:

Please write your correct name and email address. Kindly do not post any personal, abusive, defamatory, infringing, obscene, indecent, discriminatory or unlawful or similar comments. Daijiworld.com will not be responsible for any defamatory message posted under this article.

Please note that sending false messages to insult, defame, intimidate, mislead or deceive people or to intentionally cause public disorder is punishable under law. It is obligatory on Daijiworld to provide the IP address and other details of senders of such comments, to the authority concerned upon request.

Hence, sending offensive comments using daijiworld will be purely at your own risk, and in no way will Daijiworld.com be held responsible.