Brazilian Covid-19 variant much more transmissible: Study


Sao Paulo, Apr 21 (IANS): An international team of researchers has found evidence suggesting that the Brazilian coronavirus variant, the P.1 or B11248, maybe up to twice as transmissible as prior strains.

The P.1 SARS-CoV-2 variant was first seen in Manaus, the capital of the state of Amazonas in Brazil. Initial research suggested the virus arose late last year and began spreading in November. It quickly became the dominant strain and infected nearly 70 percent of the people in the city.

After variant infections rose in Manaus, the P 1 variant soon spread throughout Brazil, and then to other countries -- to date, it has been found in 37 countries, the ScienceX reported.

As per the study, published in the journal Science, the team conducted molecular clock analysis and determined that the virus had 17 identifiable mutations and that three spike protein mutations -- N501Y, E484K and K417T -- were particularly worrisome because they appeared to allow the virus to bind more tightly to human cells, and in some cases, to aid in evading antibodies.

The variant was also found to evade an immune response to prior strains of the virus. Further, simulating the virus to determine how its abilities have changed since it mutated showed the variant to be from 1.7 to 2.4 times more transmissible than previous strains of the virus.

However, the team researchers were unable to determine if the increase was due to the virus persisting longer in the body or from an increase in viral load. Also, they were not able to determine if the new variant makes people sicker or if it is deadlier. The researchers noted that more work is required to determine if the P.1 strain is truly able to infect people who have been infected with prior strains, or those who have been vaccinated.

  

Top Stories


Leave a Comment

Title: Brazilian Covid-19 variant much more transmissible: Study



You have 2000 characters left.

Disclaimer:

Please write your correct name and email address. Kindly do not post any personal, abusive, defamatory, infringing, obscene, indecent, discriminatory or unlawful or similar comments. Daijiworld.com will not be responsible for any defamatory message posted under this article.

Please note that sending false messages to insult, defame, intimidate, mislead or deceive people or to intentionally cause public disorder is punishable under law. It is obligatory on Daijiworld to provide the IP address and other details of senders of such comments, to the authority concerned upon request.

Hence, sending offensive comments using daijiworld will be purely at your own risk, and in no way will Daijiworld.com be held responsible.