Daijiworld Media Network - Boston

Boston, Aug 23: New research suggests that acetaminophen, commonly known as paracetamol, may increase the risk of autism and attention deficit hyperactivity disorder (ADHD) in children when taken during pregnancy. The study, led by researchers from Mount Sinai and Harvard’s School of Public Health, analysed data from over 100,000 participants across 46 previous studies using the Navigation Guide Systematic Review methodology.

The research examined when during pregnancy paracetamol was used—first, second, or third trimester—and correlated this with mothers’ medical records. Findings indicate that higher-quality studies are more likely to show a link between prenatal paracetamol exposure and increased risks of neurodevelopmental disorders.

Published in BMC Environmental Health, the study warns that due to the widespread use of paracetamol, even a small increase in risk could have significant public health implications.

Dr Diddier Prada, assistant professor at Mount Sinai and co-author of the study, advised, “Pregnant women should not stop taking medication without consulting their doctors. Untreated pain or fever can also harm the baby. Our study highlights the importance of discussing the safest approach with healthcare providers and considering non-drug options whenever possible.”

Previous research has also raised concerns about paracetamol, linking it to increased risks of gastrointestinal bleeding, chronic kidney disease, heart failure, and hypertension.

The study urges caution and careful medical consultation for expectant mothers considering paracetamol use.