Daijiworld Media Network – Michigan

Michigan, Sep 6: Pancreatic cancer, one of the deadliest forms of the disease, is becoming a mounting global health challenge due to its late diagnosis, aggressive nature, and limited treatment options. Now, a new study has revealed how smoking not only increases the risk but also accelerates the growth of pancreatic tumors by weakening the body’s immune defenses.

Researchers at the University of Michigan found that toxins in cigarette smoke trigger cells that release a protein called interleukin-22 (IL-22). This protein fuels aggressive tumor growth while simultaneously suppressing the body’s natural anti-tumor response, giving cancer a double advantage.

Pancreatic cancer often goes undetected in its early stages due to vague or absent symptoms. With survival rates below 20% and projections suggesting it could become the second leading cause of cancer deaths in the US by 2030, experts stress the urgent need for prevention and targeted screening.

While routine screening is not recommended for the general population, those at high risk – such as individuals with genetic mutations, a strong family history, or new-onset diabetes – are advised to undergo annual surveillance using MRI or endoscopic ultrasound. Detecting the disease early greatly improves survival chances through surgery and therapy.

Doctors emphasize that quitting smoking remains the most effective step individuals can take to lower their risk. With rising cases and grim survival statistics, researchers warn that the connection between smoking and pancreatic cancer is clearer than ever.